Faecalibacterium prausnitzii A2-165 metabolizes host- and media-derived chemicals and induces transcriptional changes in colonic epithelium in GuMI human gut microphysiological system. 

Huang, Y-J., Lewis, C.A., Wright, C., Schneider, K., Kemmitt, J., Trumper D.L., Breault D.T., Yilmaz, O., Griffith L.G., Zhang, J.* 

Microbiome Research Reports, 2024. Full text

An immune-competent human gut microphysiological system enables inflammation-modulation of Faecalibacterium prausnitzii

Zhang, J.,* Huang, Y-J.,Trapecar, M., Wright, C., Schneider, K., Kemmitt, J., Hernandez-Gordillo, V., Yoon, J.Y., Alm E.J., Breault D.T., Trumper D.L., Griffith L.G.* 

npj Biofilms and Microbiomes, 2024. Full text

Synthetic microbial communities (SynComs) of the human gut: design, assembly, and applications. 

van Leeuwen, P. T., Brul, S., Zhang, J.,* & Wortel, M. T.*. 

FEMS Microbiology Reviews, 2023. 47(2), fuad012. Full text

Human Intestinal Organoids and Microphysiological Systems for Modeling Radiotoxicity and Assessing Radioprotective Agents. 

Bouges, E., Segers, C., Leys, N., Lebeer, S., Zhang, J.,  Mastroleo, F.* 

Cancers, 2023. 15(24), p.5859.  Full text

Is acrolein a reuterin-borne chemical hazard in biopreserved foods? 

Zhang J.,* Schwab C.* 

Food Chemistry Advances, 2022: 100044. Full text

Selected Publication before 2021

Impact of manipulation of glycerol/diol dehydratase activity on intestinal microbiota ecology and metabolism. 

Ramirez Garcia A., Zhang J., Constancias F., Greppi A., Wortmann E., Wandres M., Hurley K., Pascual-García A., Ruscheweyh H.-J., Sturla S.J., Christophe Lacroix C., Schwab C. 

Environmental Microbiology 2021, 23(3), 1765–1779. Full text

Co-culture of primary human colon monolayer with human gut bacteria. 

Zhang J., Hernandez-Gordillo V., Trapecar M., Wright C., Taketani M., Schneider K., Chen W.L.K., Stas E., Breault D.T., Carrier R.L., Voigt C.A., Griffith L.G. 

Nature Protocols 2021: 1-27. Full text

Primary human colonic mucosal barrier crosstalk with super oxygen-sensitive Faecalibacterium prausnitzii in vitro. 

Zhang J.,# Huang Y.J.,# Yoon J.Y., Kemmitt J., Wright C., Schneider K., Sphabmixay P., Hernandez-Gordillo V., Holcomb S., Bhushan B., Rohatgi G., Benton K., Carpenter D., Kester J.C., Eng G., Breault D.T., Yilmaz O., Taketani M., Voigt C.A., Carrier R.L., Trumper D.L., Griffith L.G.

Med 2021, 2 (1), 74-98. Full text

Highlighted by MIT newsMed, and Nutrition Insight.

Genetic circuit design automation for the gut resident species Bacteroides thetaiotaomicron. 

Takenta M., Zhang J., Zhang Y., Triassi A., Huang Y., Griffith L.G., Voigt C. 

Nature Biotechnology, 2020, 38 (8), 962-969. Full text